Multimodal monitoring in the pediatric intensive care unit: new modalities and informatics challenges

Semin Pediatr Neurol. 2014 Dec;21(4):291-8. doi: 10.1016/j.spen.2014.10.005. Epub 2014 Oct 30.


We review several newer modalities to monitor the brain in children with acute neurologic disease in the pediatric intensive care unit, such as partial brain tissue oxygen tension (PbtO2), jugular venous oxygen saturation (SjvO2), near infrared spectroscopy (NIRS), thermal diffusion measurement of cerebral blood flow, cerebral microdialysis, and EEG. We then discuss the informatics challenges to acquire, consolidate, analyze, and display the data. Acquisition includes multiple data types: discrete, waveform, and continuous. Consolidation requires device interoperability and time synchronization. Analysis could include pressure reactivity index and quantitative EEG. Displays should communicate the patient's current status, longitudinal and trend information, and critical alarms.

Publication types

  • Review

MeSH terms

  • Brain / physiopathology*
  • Child
  • Electroencephalography
  • Humans
  • Intensive Care Units, Pediatric*
  • Microdialysis
  • Monitoring, Physiologic / methods*
  • Spectroscopy, Near-Infrared