Dietary fibre linked to decreased inflammation in overweight minority youth

Pediatr Obes. 2016 Feb;11(1):33-9. doi: 10.1111/ijpo.12017. Epub 2015 Mar 2.


Objective: The objective of this study was to examine the relationship between diet and inflammation, and adiposity in minority youth.

Design and methods: The study was designed as a cross-sectional analysis of 142 overweight (≥85th body mass index percentile) Hispanic and African-American adolescents (14-18 years) with the following measures: anthropometrics, adiposity via magnetic resonance imaging, dietary intake via 24-h dietary recalls, and inflammation markers from fasting blood draws utilizing a multiplex panel. Partial correlations were estimated and analysis of covariance (ancova) models fit to examine the relationship among dietary variables, inflammation markers and adiposity measures with the following a priori covariates: Tanner stage, ethnicity, sex, total energy intake, total body fat and total lean mass.

Results: Inference based on ancova models showed that the highest tertile of fibre intake (mean intake of 21.3 ± 6.1 g d(-1) ) vs. the lowest tertile of fibre intake (mean intake of 7.4 ± 1.8 g d(-1) ) was associated with 36% lower plasminogen activator inhibitor-1 (P = 0.02) and 43% lower resistin (P = 0.02), independent of covariates. Similar results were seen for insoluble fibre. No other dietary variables included in this study were associated with inflammation markers.

Conclusions: These results suggest that increases in dietary fibre could play an important role in lowering inflammation and therefore metabolic disease risk in high-risk minority youth.

Keywords: Adolescent; dietary fibre; inflammation; minorities; obesity; overweight.

MeSH terms

  • Adiposity
  • Adolescent
  • Black or African American*
  • Body Mass Index
  • Cross-Sectional Studies
  • Diet
  • Dietary Fiber*
  • Energy Intake
  • Fasting
  • Feeding Behavior
  • Female
  • Hispanic or Latino*
  • Humans
  • Inflammation / ethnology
  • Inflammation / etiology
  • Inflammation / prevention & control*
  • Male
  • Minority Groups
  • Overweight / complications
  • Overweight / ethnology
  • Overweight / physiopathology*
  • United States