A new approach to the treatment of asthma

N Engl J Med. 1989 Nov 30;321(22):1517-27. doi: 10.1056/NEJM198911303212206.


Asthma is a chronic inflammatory condition. The previous emphasis on bronchodilator therapy, which does not treat the underlying inflammation, may be misplaced. Earlier introduction of antiinflammatory agents, such as corticosteroids or cromolyn sodium, is strongly recommended. Effective suppression of airway inflammation reduces the need for bronchodilator therapy and may reduce the morbidity and, perhaps, mortality of asthma.

Publication types

  • Review

MeSH terms

  • Adrenergic beta-Agonists / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Asthma / drug therapy*
  • Bronchodilator Agents / therapeutic use
  • Humans


  • Adrenergic beta-Agonists
  • Anti-Inflammatory Agents
  • Bronchodilator Agents