Effect of Lonicera japonica extract on Mycoplasma gallisepticum in naturally infected broiler flocks

Br Poult Sci. 2015;56(3):299-303. doi: 10.1080/00071668.2015.1022711. Epub 2015 Apr 10.


1. In this study, the effect of chlorogenic acid extract from Lonicera japonica Thunb. on Mycoplasma gallisepticum infections and the performance of broiler flocks was investigated. 2. A total of 360 Ross-308 broiler chicks taken from M. gallisepticum seropositive flocks were divided equally into three groups designated as control (nothing administered), antibiotic (Tylosin tartrate given for the first 3 d and d 20-22) and test group (chlorogenic acid extract given twice a day on d 16 and 22). 3. Broiler performance analysis, serological tests (slide agglutination), molecular identification (polymerase chain reaction) and histopathological examination were performed to detect M. gallisepticum. 4. The results show that chlorogenic acid not only increases live body weight but is also an alternative treatment option in M. gallisepticum-infected broiler flocks.

MeSH terms

  • Agglutination Tests / veterinary
  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Chickens*
  • Female
  • Lonicera / chemistry*
  • Male
  • Mycoplasma Infections / microbiology
  • Mycoplasma Infections / prevention & control
  • Mycoplasma Infections / veterinary*
  • Mycoplasma gallisepticum / drug effects*
  • Plant Extracts / pharmacology
  • Polymerase Chain Reaction / veterinary
  • Poultry Diseases / microbiology
  • Poultry Diseases / prevention & control*


  • Anti-Bacterial Agents
  • Plant Extracts