Effects of guar gum ingestion on postprandial blood pressure in older adults

J Nutr Health Aging. 2015 Mar;19(3):299-304. doi: 10.1007/s12603-015-0453-8.

Abstract

Objectives: The aim of this study was to investigate the effects of guar gum on postprandial blood pressure in older people.

Design: A randomized, double-blind, placebo-controlled, cross-over design.

Setting: Community senior centers in B city, South Korea.

Participants: Twenty-two older female adults aged 67 to 88 with postprandial hypotension.

Intervention: The participants were randomly assigned to guar gum (semi-fluid food with 9 gram) or placebo intervention during the first treatment phase. After a washout period of 1 week, the two interventions were switched to the other in the second treatment phase.

Measurements: Blood pressure was measured during both phases before having a meal and every 15 minutes during 120 minutes after a meal with automated sphygmomanometer.

Results: Change in systolic blood pressure (SBP) over time was significantly different between guar gum and placebo groups (F=4.07, p=0.001). Compared with placebo group, guar gum group had significantly low prevalence of postprandial hypotension (PPH) (guar gum group=18.2% vs. placebo group=72.7%; χ² =13.20, p<0.001). It also had significant difference in change of diastolic blood pressure (DBP) over time between guar gum and placebo groups (F=2.49, p=0.027).

Conclusion: This findings show that guar gum could be effective on postprandial drops in blood pressure in older female adults.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Pressure / drug effects*
  • Blood Pressure / physiology
  • Cross-Over Studies
  • Double-Blind Method
  • Female
  • Galactans / pharmacology*
  • Galactans / therapeutic use
  • Humans
  • Hypotension / diet therapy*
  • Hypotension / physiopathology
  • Mannans / pharmacology*
  • Mannans / therapeutic use
  • Plant Gums / pharmacology*
  • Plant Gums / therapeutic use
  • Postprandial Period / drug effects*
  • Postprandial Period / physiology*
  • Republic of Korea

Substances

  • Galactans
  • Mannans
  • Plant Gums
  • guar gum