Prevalence of Chlamydia Trachomatis Infection in Samoan Women Aged 18 to 29 and Assessment of Possible Risk Factors: A Community-Based Study

Trans R Soc Trop Med Hyg. 2015 Apr;109(4):245-51. doi: 10.1093/trstmh/trv014. Epub 2015 Mar 1.

Abstract

Background: Knowledge about genital Chlamydia trachomatis (CT) infections in the Pacific is limited. In this study we investigated CT infection in Samoan women.

Methods: We recruited women having unprotected sex aged 18 to 29 years from 41 Samoan villages. They completed a questionnaire and provided a urine sample for CT testing by PCR. Associations between CT infection and possible risk factors were explored using logistic regression.

Results: Altogether, 239 women were recruited; 86 (36.0%; weighted estimate of prevalence: 41.9%; 95% CI: 33.4-50.5%) were positive for CT infection. A higher proportion of women aged 18 to 24 were positive (54/145; 37.2%) than those aged 25 to 29 (32/94; 34.0%; p=0.20). Being single (OR 1.92; 95% CI: 1.02-3.63) and having two or more lifetime sexual partners (OR 3.02; 95% CI: 1.19-7.67) were associated with CT infection; 27.6% of those with one lifetime partner were positive. Participants who had a previous pregnancy were less likely to be positive (OR 0.49; 95% CI: 0.27-0.87). Primiparous and multiparous women were less likely to be positive than nulliparous women (OR 0.54; 95% CI: 0.30-0.99 and OR 0.46; 95% CI: 0.24-0.89, respectively).

Conclusions: The prevalence of CT infection in these Samoan women is very high. Further studies, including investigating the prevalence of CT infection in men, and strategies for sustainable control are needed.

Keywords: Chlamydia trachomatis; Genital; Prevalence; Risk factors.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / administration & dosage*
  • Azithromycin / administration & dosage*
  • Chlamydia Infections / epidemiology
  • Chlamydia Infections / prevention & control*
  • Chlamydia Infections / urine
  • Chlamydia trachomatis / isolation & purification*
  • Cluster Analysis
  • Cross-Sectional Studies
  • Health Education / organization & administration*
  • Humans
  • Mass Screening / organization & administration*
  • Prevalence
  • Reproductive Health / education
  • Risk Factors
  • Samoa / epidemiology
  • Sexual Behavior / psychology
  • Sexual Partners
  • Surveys and Questionnaires
  • Unsafe Sex

Substances

  • Anti-Bacterial Agents
  • Azithromycin