Inflammation. Potent small molecule extinguishes the NLRP3 inflammasome

Nat Rev Rheumatol. 2015 Apr;11(4):198. doi: 10.1038/nrrheum.2015.23. Epub 2015 Mar 3.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Carrier Proteins / antagonists & inhibitors*
  • Cryopyrin-Associated Periodic Syndromes / drug therapy*
  • Encephalomyelitis, Autoimmune, Experimental / drug therapy*
  • Heterocyclic Compounds, 4 or More Rings / therapeutic use*
  • Humans
  • Inflammasomes / antagonists & inhibitors*
  • Interleukin-1beta / drug effects*
  • Multiple Sclerosis*
  • Sulfones / therapeutic use*

Substances

  • Carrier Proteins
  • Heterocyclic Compounds, 4 or More Rings
  • Inflammasomes
  • Interleukin-1beta
  • Sulfones