Abstract
Bone and the immune system interact with each other and share molecular mechanisms to maintain the homeostasis. The paradigm of the osteoimmune system is required for both bone biology and immunology, providing an essential framework for understanding the physiology and pathology of metabolic bone diseases and immunological disorders.
Copyright © 2015 Elsevier Inc. All rights reserved.
MeSH terms
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Bone Diseases, Metabolic / immunology
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Bone Diseases, Metabolic / pathology
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Bone and Bones / immunology
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Bone and Bones / physiology
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Homeostasis / immunology
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Homeostasis / physiology
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Humans
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Immune System / immunology*
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Immune System / pathology*
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Immune System Diseases / immunology
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Immune System Diseases / pathology
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Osteoclasts / immunology*
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Osteoclasts / pathology*
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Signal Transduction / immunology
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Signal Transduction / physiology