SnapShot: Osteoimmunology

Hiroshi Takayanagi

doi:10.1016/j.cmet.2015.02.001

SnapShot: Osteoimmunology

Cell Metab. 2015 Mar 3;21(3):502.e1. doi: 10.1016/j.cmet.2015.02.001.

Author

Hiroshi Takayanagi¹

Affiliation

¹ Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan and Japan Science and Technology Agency (JST), Exploratory Research for Advanced Technology (ERATO) Program, Takayanagi Osteonetwork Project, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan.

PMID: 25738464
DOI: 10.1016/j.cmet.2015.02.001

Abstract

Bone and the immune system interact with each other and share molecular mechanisms to maintain the homeostasis. The paradigm of the osteoimmune system is required for both bone biology and immunology, providing an essential framework for understanding the physiology and pathology of metabolic bone diseases and immunological disorders.

MeSH terms

Bone Diseases, Metabolic / immunology
Bone Diseases, Metabolic / pathology
Bone and Bones / immunology
Bone and Bones / physiology
Homeostasis / immunology
Homeostasis / physiology
Humans
Immune System / immunology*
Immune System / pathology*
Immune System Diseases / immunology
Immune System Diseases / pathology
Osteoclasts / immunology*
Osteoclasts / pathology*
Signal Transduction / immunology
Signal Transduction / physiology