Long-term green tea extract supplementation does not affect fat absorption, resting energy expenditure, and body composition in adults

J Nutr. 2015 May;145(5):864-70. doi: 10.3945/jn.114.207829. Epub 2015 Mar 4.


Background: Green tea (GT) extract may play a role in body weight regulation. Suggested mechanisms are decreased fat absorption and increased energy expenditure.

Objective: We examined whether GT supplementation for 12 wk has beneficial effects on weight control via a reduction in dietary lipid absorption as well as an increase in resting energy expenditure (REE).

Methods: Sixty Caucasian men and women [BMI (in kg/m²): 18-25 or >25; age: 18-50 y] were included in a randomized placebo-controlled study in which fecal energy content (FEC), fecal fat content (FFC), resting energy expenditure, respiratory quotient (RQ), body composition, and physical activity were measured twice (baseline vs. week 12). For 12 wk, subjects consumed either GT (>0.56 g/d epigallocatechin gallate + 0.28-0.45 g/d caffeine) or placebo capsules. Before the measurements, subjects recorded energy intake for 4 consecutive days and collected feces for 3 consecutive days.

Results: No significant differences between groups and no significant changes over time were observed for the measured variables. Overall means ± SDs were 7.2 ± 3.8 g/d, 6.1 ± 1.2 MJ/d, 67.3 ± 14.3 kg, and 29.8 ± 8.6% for FFC, REE, body weight, and body fat percentage, respectively.

Conclusion: GT supplementation for 12 wk in 60 men and women did not have a significant effect on FEC, FFC, REE, RQ, and body composition.

Trial registration: ClinicalTrials.gov NCT01556321.

Keywords: body composition; fat absorption; green tea; long-term effects; resting energy expenditure.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adiposity
  • Adolescent
  • Adult
  • Anti-Obesity Agents / therapeutic use*
  • Basal Metabolism
  • Body Mass Index
  • Camellia sinensis / chemistry*
  • Dietary Fats / antagonists & inhibitors
  • Dietary Fats / metabolism*
  • Dietary Supplements*
  • Feces / chemistry
  • Female
  • Food Handling
  • Gastrointestinal Agents / therapeutic use
  • Humans
  • Intestinal Absorption*
  • Male
  • Middle Aged
  • Overweight / metabolism
  • Overweight / prevention & control*
  • Plant Extracts / therapeutic use*
  • Plant Leaves / chemistry
  • Single-Blind Method
  • Young Adult


  • Anti-Obesity Agents
  • Dietary Fats
  • Gastrointestinal Agents
  • Plant Extracts

Associated data

  • ClinicalTrials.gov/NCT01556321