Abstract
The radiologic findings of a single nodule from Pneumocystis jirovecii pneumonia (PJP) have been rarely reported. We described a case of granulomatous PJP manifesting as a solitary pulmonary nodule with a halo sign in a 69-year-old woman with diffuse large B cell lymphoma during chemotherapy. The radiologic appearance of the patient suggested an infectious lesion such as angioinvasive pulmonary aspergillosis or lymphoma involvement of the lung; however, clinical manifestations were not compatible with the diseases. The nodule was confirmed as granulomatous PJP by video-assisted thoracoscopic surgery biopsy.
Keywords:
Granulomatous Pneumocystis jirovecii pneumonia; Lymphoma; Nodular opacity.
MeSH terms
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Aged
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Antibodies, Monoclonal, Murine-Derived / adverse effects
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Antibodies, Monoclonal, Murine-Derived / therapeutic use
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Antineoplastic Agents / adverse effects
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Antineoplastic Agents / therapeutic use
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Antineoplastic Combined Chemotherapy Protocols / adverse effects
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Biopsy / methods
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Cyclophosphamide / adverse effects
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Cyclophosphamide / therapeutic use
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Doxorubicin / adverse effects
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Doxorubicin / therapeutic use
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Female
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Humans
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Lymphoma, Large B-Cell, Diffuse / drug therapy
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Lymphoma, Large B-Cell, Diffuse / microbiology
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Pneumocystis carinii / pathogenicity
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Pneumonia, Pneumocystis / diagnosis*
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Pneumonia, Pneumocystis / diagnostic imaging*
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Positron-Emission Tomography
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Prednisone / adverse effects
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Prednisone / therapeutic use
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Rituximab
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Solitary Pulmonary Nodule / microbiology*
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Thoracic Surgery, Video-Assisted
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Tomography, X-Ray Computed
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Vincristine / adverse effects
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Vincristine / therapeutic use
Substances
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Antibodies, Monoclonal, Murine-Derived
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Antineoplastic Agents
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R-CHOP protocol
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Rituximab
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisone