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Review
. 2015 Feb 19:6:74.
doi: 10.3389/fimmu.2015.00074. eCollection 2015.

5' tRNA Halves: The Next Generation of Immune Signaling Molecules

Affiliations
Free PMC article
Review

5' tRNA Halves: The Next Generation of Immune Signaling Molecules

Joseph Mohsen Dhahbi. Front Immunol. .
Free PMC article
No abstract available

Keywords: 5′ tRNA halves; circulating 5′ tRNA halves; extracellular small non-coding RNAs; small non-coding RNAs; tRNA-derived small RNAs.

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Figures

Figure 1
Figure 1
Tissue distribution of tRNA–Gly–GCC halves. Northern blotting analysis of RNA extracted from the indicated mouse tissues (A–C) or from human leukocytes or serum (D). Blots were analyzed with 5’ end probes of tRNA–Gly–GCC. DM, decade markers. This figure is an edited version of Figure 7 in Ref. (22).

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References

    1. Rother S, Meister G. Small RNAs derived from longer non-coding RNAs. Biochimie (2011) 93(11):1905–1510.1016/j.biochi.2011.07.032 - DOI - PubMed
    1. Sobala A, Hutvagner G. Transfer RNA-derived fragments: origins, processing, and functions. Wiley Interdiscip Rev RNA (2011) 2(6):853–62.10.1002/wrna.96 - DOI - PubMed
    1. Lee YS, Shibata Y, Malhotra A, Dutta A. A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). Genes Dev (2009) 23(22):2639–49.10.1101/gad.1837609 - DOI - PMC - PubMed
    1. Martens-Uzunova ES, Olvedy M, Jenster G. Beyond microRNA – novel RNAs derived from small non-coding RNA and their implication in cancer. Cancer Lett (2013) 340(2):201–11.10.1016/j.canlet.2012.11.058 - DOI - PubMed
    1. Wang Q, Lee I, Ren J, Ajay SS, Lee YS, Bao X. Identification and functional characterization of tRNA-derived RNA fragments (tRFs) in respiratory syncytial virus infection. Mol Ther (2013) 21(2):368–79.10.1038/mt.2012.237 - DOI - PMC - PubMed