Intranasal dexmedetomidine for sedation for pediatric computed tomography imaging

J Pediatr. 2015 May;166(5):1313-1315.e1. doi: 10.1016/j.jpeds.2015.01.036. Epub 2015 Mar 6.

Abstract

This prospective observational pilot study evaluated the aerosolized intranasal route for dexmedetomidine as a safe, effective, and efficient option for infant and pediatric sedation for computed tomography imaging. The mean time to sedation was 13.4 minutes, with excellent image quality, no failed sedations, or significant adverse events.

Trial registration: Registered with ClinicalTrials.gov: NCT01900405.

Publication types

  • Observational Study

MeSH terms

  • Administration, Intranasal
  • Aerosols
  • Child, Preschool
  • Conscious Sedation / methods*
  • Dexmedetomidine / administration & dosage*
  • Female
  • Hemodynamics
  • Humans
  • Hypnotics and Sedatives / administration & dosage
  • Infant
  • Male
  • Pilot Projects
  • Prospective Studies
  • Tomography, X-Ray Computed*

Substances

  • Aerosols
  • Hypnotics and Sedatives
  • Dexmedetomidine

Associated data

  • ClinicalTrials.gov/NCT01900405