This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Email citation

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Comment

. 2015 Jun 6;385(9984):2227-9.

doi: 10.1016/S0140-6736(14)61931-0. Epub 2015 Mar 4.

Statin treatment: can genetics sharpen the focus?

Heribert Schunkert¹, Nilesh J Samani²

Affiliations

Affiliations

¹ Deutsches Herzzentrum München and Technische Universität München, DZHK Munich Heart Alliance, D-80636 Munich, Germany. Electronic address: schunkert@dhm.mhn.de.
² Department of Cardiovascular Sciences, University of Leicester, and NIHR Leicester Cardiovascular Biomedical Research Unit, BHF Cardiovascular Research Centre, Leicester, UK.

PMID: 25748613
DOI: 10.1016/S0140-6736(14)61931-0

Comment

Statin treatment: can genetics sharpen the focus?

Heribert Schunkert et al. Lancet. 2015.

. 2015 Jun 6;385(9984):2227-9.

doi: 10.1016/S0140-6736(14)61931-0. Epub 2015 Mar 4.

Authors

Heribert Schunkert¹, Nilesh J Samani²

Affiliations

¹ Deutsches Herzzentrum München and Technische Universität München, DZHK Munich Heart Alliance, D-80636 Munich, Germany. Electronic address: schunkert@dhm.mhn.de.
² Department of Cardiovascular Sciences, University of Leicester, and NIHR Leicester Cardiovascular Biomedical Research Unit, BHF Cardiovascular Research Centre, Leicester, UK.

PMID: 25748613
DOI: 10.1016/S0140-6736(14)61931-0

No abstract available

PubMed Disclaimer

Comment on

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
Mega JL, Stitziel NO, Smith JG, Chasman DI, Caulfield M, Devlin JJ, Nordio F, Hyde C, Cannon CP, Sacks F, Poulter N, Sever P, Ridker PM, Braunwald E, Melander O, Kathiresan S, Sabatine MS. Mega JL, et al. Lancet. 2015 Jun 6;385(9984):2264-2271. doi: 10.1016/S0140-6736(14)61730-X. Epub 2015 Mar 4. Lancet. 2015. PMID: 25748612 Free PMC article.

Similar articles

Genetics: Genetic risk scores--new promises for drug evaluation.
Jukema JW, Trompet S. Jukema JW, et al. Nat Rev Cardiol. 2015 Jun;12(6):321-2. doi: 10.1038/nrcardio.2015.62. Epub 2015 Apr 21. Nat Rev Cardiol. 2015. PMID: 25898262 No abstract available.
Association of a Family History of Coronary Heart Disease With Initiation of Statin Therapy in Individuals at Intermediate Risk: Post Hoc Analysis of a Randomized Clinical Trial.
Safarova MS, Bailey KR, Kullo IJ. Safarova MS, et al. JAMA Cardiol. 2016 Jun 1;1(3):364-6. doi: 10.1001/jamacardio.2016.0227. JAMA Cardiol. 2016. PMID: 27438122 Clinical Trial. No abstract available.
[Less (pulmonary embolism) recurrence through longer oral anticoagulation].
Gohlke H. Gohlke H. Dtsch Med Wochenschr. 2015 Sep;140(19):1416. doi: 10.1055/s-0041-103233. Epub 2015 Sep 24. Dtsch Med Wochenschr. 2015. PMID: 26402171 German. No abstract available.
The large clinical statin trials.
Agewall S. Agewall S. Int J Cardiol. 2011 Jul 1;150(1):108-11. doi: 10.1016/j.ijcard.2011.04.029. Epub 2011 May 28. Int J Cardiol. 2011. PMID: 21621286 Review. No abstract available.
[Statin therapy is a basic treatment for coronary heart disease].
Gurevich MA. Gurevich MA. Klin Med (Mosk). 2003;81(12):60-2. Klin Med (Mosk). 2003. PMID: 14971160 Review. Russian.

See all similar articles

Cited by

Genome Editing in Dyslipidemia and Atherosclerosis.
Chen Z, Lehertshuber C, Schunkert H. Chen Z, et al. Adv Exp Med Biol. 2023;1396:139-156. doi: 10.1007/978-981-19-5642-3_10. Adv Exp Med Biol. 2023. PMID: 36454465 Review.
Using a Polygenic Score to Predict the Risk of Developing Primary Osteoporosis.
Yalaev B, Tyurin A, Prokopenko I, Karunas A, Khusnutdinova E, Khusainova R. Yalaev B, et al. Int J Mol Sci. 2022 Sep 2;23(17):10021. doi: 10.3390/ijms231710021. Int J Mol Sci. 2022. PMID: 36077420 Free PMC article.
Risk Prediction of Cardiovascular Events by Exploration of Molecular Data with Explainable Artificial Intelligence.
Westerlund AM, Hawe JS, Heinig M, Schunkert H. Westerlund AM, et al. Int J Mol Sci. 2021 Sep 24;22(19):10291. doi: 10.3390/ijms221910291. Int J Mol Sci. 2021. PMID: 34638627 Free PMC article. Review.
Inflammation-Related Risk Loci in Genome-Wide Association Studies of Coronary Artery Disease.
Mauersberger C, Schunkert H, Sager HB. Mauersberger C, et al. Cells. 2021 Feb 19;10(2):440. doi: 10.3390/cells10020440. Cells. 2021. PMID: 33669721 Free PMC article. Review.
Polygenic risk scores: from research tools to clinical instruments.
Lewis CM, Vassos E. Lewis CM, et al. Genome Med. 2020 May 18;12(1):44. doi: 10.1186/s13073-020-00742-5. Genome Med. 2020. PMID: 32423490 Free PMC article. Review.

See all "Cited by" articles

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions

Substances

Actions

LinkOut - more resources

Full Text Sources
- ClinicalKey
- Elsevier Science
Medical
- MedlinePlus Health Information