Drugging the gut microbiome

Nat Biotechnol. 2015 Mar;33(3):228-31. doi: 10.1038/nbt.3161.


Using conventional drug discovery and novel synthetic biology approaches, some investigators and companies are mining our resident microbes and their metabolites for targets in small-molecule drug programs. Ken Garber reports.

MeSH terms

  • Cardiovascular Diseases / therapy
  • Drug Discovery*
  • Fermentation
  • Gastrointestinal Microbiome*
  • Genetic Engineering
  • Humans
  • Metabolome