Interventions for Sleep Disturbance in Bipolar Disorder

Sleep Med Clin. 2015 Mar;10(1):101-5. doi: 10.1016/j.jsmc.2014.11.005.


Bipolar disorder is a severe and chronic disorder, ranked in the top 10 leading causes of disability worldwide. Sleep disturbances are strongly coupled with interepisode dysfunction and symptom worsening in bipolar disorder. Experimental studies suggest that sleep deprivation can trigger manic relapse. There is evidence that sleep deprivation can have an adverse impact on emotion regulation the following day. The clinical management of the sleep disturbances experienced by bipolar patients, including insomnia, hypersomnia delayed sleep phase, and irregular sleep-wake schedule, may include medication approaches, psychological interventions, light therapies and sleep deprivation.

MeSH terms

  • Bipolar Disorder / complications
  • Bipolar Disorder / physiopathology*
  • Bipolar Disorder / therapy*
  • Humans
  • Sleep / physiology
  • Sleep Wake Disorders / complications
  • Sleep Wake Disorders / physiopathology*
  • Sleep Wake Disorders / therapy*