Radiation therapy at compact Compton sources

Phys Med. 2015 Sep;31(6):596-600. doi: 10.1016/j.ejmp.2015.02.010. Epub 2015 Mar 6.

Abstract

The principle of the compact Compton source is presented briefly. In collision with an ultrarelativistic electron bunch a laser pulse is back-scattered as hard X-rays. The radiation cone has an opening of a few mrad, and the energy bandwidth is a few percent. The electrons that have an energy of the order of a few tens of MeV either circulate in storage ring, or are injected to a linac at a frequency of 10-100 MHz. At the interaction point the electron bunch collides with the laser pulse that has been amplified in a Fabry-Perot resonator. There are several machines in design or construction phase, and projected fluxes are 10(12) to 10(14) photons/s. The flux available at 80 keV from the ThomX machine is compared with that used in the Stereotactic Synchrotron Radiation Therapy clinical trials. It is concluded that ThomX has the potential of serving as the radiation source in future radiation therapy programs, and that ThomX can be integrated in hospital environment.

Keywords: Compton source; Radiation therapy; X-rays.

Publication types

  • Review

MeSH terms

  • Animals
  • Dose Fractionation, Radiation*
  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Miniaturization
  • Radiotherapy, High-Energy / instrumentation*
  • Radiotherapy, High-Energy / methods*
  • Synchrotrons / instrumentation*
  • Technology Assessment, Biomedical