Screening for Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium should it be integrated into routine pregnancy care in French young pregnant women?

Diagn Microbiol Infect Dis. 2015 May;82(1):14-9. doi: 10.1016/j.diagmicrobio.2015.01.014. Epub 2015 Feb 3.


Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium screening during pregnancy is not performed routinely in France. We conducted the first prospective study in 1004 women attending for routine antenatal care to determine the prevalence and risk factors for these bacterial infections. The overall prevalence of C. trachomatis, N. gonorrhoeae, and M. genitalium infections was 2.5%, 0%, and 0.8%, respectively. In patients aged 18-24 years, the prevalence increased to 7.9% for C. trachomatis and to 2.4% for M. genitalium. C. trachomatis infection was associated with age ≤24 years or being single or having more than 5 sexual partners in a lifetime. M. genitalium infection was more frequent in patients aged ≤24 years or who had a history of abortion or their first sexual intercourse after 20 years of age. The high prevalence of C. trachomatis in pregnant women aged ≤24 years, mostly asymptomatic, suggests that systematic screening could be beneficial.

Keywords: Chlamydia trachomatis; Mycoplasma genitalium; Neisseria gonorrhoeae; Pregnancy; Prevalence; Risk factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Chlamydia Infections / diagnosis
  • Chlamydia Infections / epidemiology*
  • Chlamydia trachomatis / isolation & purification
  • Diagnostic Tests, Routine / methods*
  • Female
  • France / epidemiology
  • Gonorrhea / diagnosis
  • Gonorrhea / epidemiology*
  • Humans
  • Mycoplasma Infections / diagnosis
  • Mycoplasma Infections / epidemiology*
  • Mycoplasma genitalium / isolation & purification
  • Neisseria gonorrhoeae / isolation & purification
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • Prenatal Diagnosis / methods*
  • Prevalence
  • Prospective Studies
  • Young Adult