Our interface with the built environment: immunity and the indoor microbiota

Trends Immunol. 2015 Mar;36(3):121-3. doi: 10.1016/j.it.2015.01.001.


The rise of urbanization and an increasingly indoor lifestyle has affected human interactions with our microbiota in unprecedented ways. We discuss how this lifestyle may influence immune development and function, and argue that it is time that we examined ways to manipulate the indoor environment to increase our exposure to a wider phylogeny of microorganisms. An important step is to continue to engage citizen scientists in the efforts to characterize our interactions with the diverse microbial environments that we inhabit.

Keywords: built environment; microbiome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ecological Systems, Closed
  • Environment
  • Environment Design / trends
  • Humans
  • Immunity*
  • Information Dissemination
  • Metagenome / immunology*
  • Microbiota / immunology*
  • Social Media
  • Symbiosis / immunology*
  • Urbanization / trends