[Evaluation of the efficacy of the magnesium salt of N-acetyl-aspartyl-glutamic acid in the treatment of acute rhinitis]

Clin Ter. 1989 Nov 15;131(3):173-6.
[Article in Italian]

Abstract

The object of the above study was to evaluate the tolerability and possible therapeutic use of MgNAAGA (Mg salt of N-acetyl-aspartyl-glutamic acid) in patients with allergic rhinitis. Out of 22 subjects with respiratory allergy, 12 were treated for 15 days with MgNAAGA and 10 with DSCG for the same length of time. During this period, patients kept a diary in which they recorded the following symptoms: rhinorrhea, itching, sneezing and nasal obstruction. The trial drug was found to be well tolerated and not to give rise to relevant side effects. The therapeutic efficacy was similar to that of DSCG.

Publication types

  • Comparative Study

MeSH terms

  • Administration, Intranasal
  • Adolescent
  • Adult
  • Cromolyn Sodium / therapeutic use
  • Dipeptides / administration & dosage
  • Dipeptides / therapeutic use*
  • Drug Evaluation
  • Histamine H1 Antagonists / administration & dosage
  • Histamine H1 Antagonists / therapeutic use*
  • Humans
  • Rhinitis, Allergic, Perennial / drug therapy*
  • Rhinitis, Allergic, Seasonal / drug therapy*

Substances

  • Dipeptides
  • Histamine H1 Antagonists
  • isospaglumic acid
  • Cromolyn Sodium