Pachychoroid diseases of the macula

Review

. 2014 Winter;3(4):111-5.

Pachychoroid diseases of the macula

Roberto Gallego-Pinazo¹, Rosa Dolz-Marco¹, Francisco Gómez-Ulla², Sarah Mrejen³, K Bailey Freund⁴

Affiliations

¹ Unit of Macula, Department of Ophthalmology, University and Polytechnic Hospital La Fe, Valencia, Spain ; RETICS Oftared, Health Institute Carlos III, Madrid, Spain.
² RETICS Oftared, Health Institute Carlos III, Madrid, Spain ; Department of Ophthalmology, University of Santiago de Compostela, Santiago de Compostela, Spain ; Ophthalmic Institute Gomez-Ulla, Santiago de Compostela, Spain.
³ Vitreous, Retina, Macula Consultants of New York, New York, USA ; LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, USA.
⁴ Vitreous, Retina, Macula Consultants of New York, New York, USA ; LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, USA ; Department of Ophthalmology, New York University School of Medicine, New York, USA.

PMID: 25756060
PMCID: PMC4352204

Free PMC article

Review

Pachychoroid diseases of the macula

Roberto Gallego-Pinazo et al. Med Hypothesis Discov Innov Ophthalmol. 2014 Winter.

Free PMC article

. 2014 Winter;3(4):111-5.

Authors

Roberto Gallego-Pinazo¹, Rosa Dolz-Marco¹, Francisco Gómez-Ulla², Sarah Mrejen³, K Bailey Freund⁴

Affiliations

¹ Unit of Macula, Department of Ophthalmology, University and Polytechnic Hospital La Fe, Valencia, Spain ; RETICS Oftared, Health Institute Carlos III, Madrid, Spain.
² RETICS Oftared, Health Institute Carlos III, Madrid, Spain ; Department of Ophthalmology, University of Santiago de Compostela, Santiago de Compostela, Spain ; Ophthalmic Institute Gomez-Ulla, Santiago de Compostela, Spain.
³ Vitreous, Retina, Macula Consultants of New York, New York, USA ; LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, USA.
⁴ Vitreous, Retina, Macula Consultants of New York, New York, USA ; LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, USA ; Department of Ophthalmology, New York University School of Medicine, New York, USA.

PMID: 25756060
PMCID: PMC4352204

Abstract

Advances in optical coherence tomography have enabled a better appreciation of the role of pathologic choroidal changes in a variety of retinal disease. A "pachychoroid" (pachy-[prefix]: thick) is defined as an abnormal and permanent increase in choroidal thickness often showing dilated choroidal vessels and other structural alterations of the normal choroidal architecture. Central serous chorioretinopathy is just one of several pachychoroid-related macular disorders. This review summarizes the current state of knowledge of the pachycoroid spectrum and the hallmark features seen with multimodal imaging analysis of these entities.

Keywords: Central serous chorioretinopathy; Macula; Pachychoroid Diseases.

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Figures

**Figure 1.**
Forty year-old man with typical CSC

**Figure 2**
Morphologic changes identified in the OCT images of cases with PPE

**Figure 3**
Fifty-three-year-old man with typical changes of pachychoroid neovasculopathy

See this image and copyright information in PMC

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References

1. Huang D, Swanson EA, Lin CP, Schuman JS, Stinson WG, Chang W, Hee MR, Flotte T, Gregory K, Puliafito CA, et al. Optical coherence tomography. Science. 1991 Nov;254(5035):1178–81. PMID: 1957169. - PMC - PubMed
1. Swanson EA, Izatt JA, Hee MR, Huang D, Lin CP, Schuman JS, Puliafito CA, Fujimoto JG. In vivo retinal imaging by optical coherence tomography. Opt Lett. 1993 Nov;18(21):1864–6. PMID: 19829430. - PubMed
1. Toth CA, Narayan DG, Boppart SA, Hee MR, Fujimoto JG, Birngruber R, Cain CP, DiCarlo CD, Roach WP. A comparison of retinal morphology viewed by optical coherence tomography and by light microscopy. Arch Ophthalmol. 1997 Nov;115(11):1425–8. PMID: 9366674. - PubMed
1. Drexler W, Morgner U, Ghanta RK, Kärtner FX, Schuman JS, Fujimoto JG. Ultrahigh-resolution ophthalmic optical coherence tomography. Nat Med. 2001 Apr;7(4):502–7. Erratum in: Nat Med 2001 May;7(5):636. PMID: 11283681. - PMC - PubMed
1. Gloesmann M, Hermann B, Schubert C, Sattmann H, Ahnelt PK, Drexler W. Histologic correlation of pig retina radial stratification with ultrahigh-resolution optical coherence tomography. Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1696–703. PMID: 12657611. - PubMed

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[1] Huang D, Swanson EA, Lin CP, Schuman JS, Stinson WG, Chang W, Hee MR, Flotte T, Gregory K, Puliafito CA, et al. Optical coherence tomography. Science. 1991 Nov;254(5035):1178–81. PMID: 1957169. - PMC - PubMed

[2] Huang D, Swanson EA, Lin CP, Schuman JS, Stinson WG, Chang W, Hee MR, Flotte T, Gregory K, Puliafito CA, et al. Optical coherence tomography. Science. 1991 Nov;254(5035):1178–81. PMID: 1957169. - PMC - PubMed

[3] Swanson EA, Izatt JA, Hee MR, Huang D, Lin CP, Schuman JS, Puliafito CA, Fujimoto JG. In vivo retinal imaging by optical coherence tomography. Opt Lett. 1993 Nov;18(21):1864–6. PMID: 19829430. - PubMed

[4] Swanson EA, Izatt JA, Hee MR, Huang D, Lin CP, Schuman JS, Puliafito CA, Fujimoto JG. In vivo retinal imaging by optical coherence tomography. Opt Lett. 1993 Nov;18(21):1864–6. PMID: 19829430. - PubMed

[5] Toth CA, Narayan DG, Boppart SA, Hee MR, Fujimoto JG, Birngruber R, Cain CP, DiCarlo CD, Roach WP. A comparison of retinal morphology viewed by optical coherence tomography and by light microscopy. Arch Ophthalmol. 1997 Nov;115(11):1425–8. PMID: 9366674. - PubMed

[6] Toth CA, Narayan DG, Boppart SA, Hee MR, Fujimoto JG, Birngruber R, Cain CP, DiCarlo CD, Roach WP. A comparison of retinal morphology viewed by optical coherence tomography and by light microscopy. Arch Ophthalmol. 1997 Nov;115(11):1425–8. PMID: 9366674. - PubMed

[7] Drexler W, Morgner U, Ghanta RK, Kärtner FX, Schuman JS, Fujimoto JG. Ultrahigh-resolution ophthalmic optical coherence tomography. Nat Med. 2001 Apr;7(4):502–7. Erratum in: Nat Med 2001 May;7(5):636. PMID: 11283681. - PMC - PubMed

[8] Drexler W, Morgner U, Ghanta RK, Kärtner FX, Schuman JS, Fujimoto JG. Ultrahigh-resolution ophthalmic optical coherence tomography. Nat Med. 2001 Apr;7(4):502–7. Erratum in: Nat Med 2001 May;7(5):636. PMID: 11283681. - PMC - PubMed

[9] Gloesmann M, Hermann B, Schubert C, Sattmann H, Ahnelt PK, Drexler W. Histologic correlation of pig retina radial stratification with ultrahigh-resolution optical coherence tomography. Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1696–703. PMID: 12657611. - PubMed

[10] Gloesmann M, Hermann B, Schubert C, Sattmann H, Ahnelt PK, Drexler W. Histologic correlation of pig retina radial stratification with ultrahigh-resolution optical coherence tomography. Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1696–703. PMID: 12657611. - PubMed

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Pachychoroid diseases of the macula

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Pachychoroid diseases of the macula

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