[Digestive enzyme activity during immobilization stress and its pharmacologic correction with adrenoblockaders]

Patol Fiziol Eksp Ter. Nov-Dec 1989;(6):49-52.
[Article in Russian]

Abstract

The change from relative digestive rest to the phase of digestion is characterized by various dynamics of the activity of enterokinase, amylase, and intestinal isoenzyme of alkaline phosphatase. The effect of the food stimulus in 3-hour immobilization can be considered antistress because the activity of the intestinal enzymes is almost the same as that in intact animals. It was found that the intestinal digestive enzymes become adapted to repeated short-term immobilization stress. Administration of alpha- and beta-adrenergic blocking agents changes the response of the digestive enzymes to stress by lowering their activity.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adrenergic alpha-Antagonists / therapeutic use*
  • Animals
  • Digestion / drug effects
  • Digestion / physiology*
  • Dioxanes / therapeutic use*
  • Dioxins / therapeutic use*
  • Drug Evaluation, Preclinical
  • Female
  • Intestines / drug effects
  • Intestines / enzymology
  • Male
  • Propranolol / therapeutic use*
  • Rats
  • Restraint, Physical
  • Stress, Psychological / drug therapy
  • Stress, Psychological / enzymology*
  • Time Factors

Substances

  • Adrenergic alpha-Antagonists
  • Dioxanes
  • Dioxins
  • Propranolol
  • proroxan