H10N8 and H6N1 maintain avian receptor binding

Cell Host Microbe. 2015 Mar 11;17(3):292-294. doi: 10.1016/j.chom.2015.02.020.


Influenza viruses of animals can cross species and infect humans. In this issue of Cell Host & Microbe, Zhang et al. (2015) and Tzarum et al. (2015) describe crystal structures and receptor-binding properties of hemagglutinins of avian-origin H10N8 and H6N1 influenza viruses. Human infections with these viruses are not associated with a switch favoring human receptor binding.

Publication types

  • Comment

MeSH terms

  • Hemagglutinin Glycoproteins, Influenza Virus / chemistry*
  • Hemagglutinin Glycoproteins, Influenza Virus / metabolism*
  • Humans
  • Influenza A Virus, H10N8 Subtype / physiology*
  • Influenza A virus / chemistry*
  • Influenza A virus / physiology*
  • Influenza, Human / virology*
  • Receptors, Virus / metabolism*
  • Sialic Acids / metabolism*
  • Virus Attachment*


  • Hemagglutinin Glycoproteins, Influenza Virus
  • Receptors, Virus
  • Sialic Acids