Oxygen uptake and heart rate kinetics during dynamic upper and lower body exercise: an investigation by time-series analysis

Eur J Appl Physiol. 2015 Aug;115(8):1665-72. doi: 10.1007/s00421-015-3146-4. Epub 2015 Mar 13.

Abstract

Purpose: The study compared the kinetic responses of heart rate (HR), pulmonary ([Formula: see text]O2pulm) and muscular oxygen uptake ([Formula: see text]O2musc) for upper (UpBody) and lower body (LoBody) exercise.

Methods: Eleven healthy men (24 ± 2 years, 184 ± 8 cm, 79 ± 7 kg) performed pseudo-random binary sequence (PRBS) work rate (WR) changes on a semi-recumbent cycle ergometer (30 and 80 W) and an arm cranking exercise device (20 and 50 W); followed by stepwise increases in WR (UpBody: 20 W 5 min(-1); LoBody: 50 W 5 min(-1)). [Formula: see text]O2pulm was measured breath-by-breath and HR beat-to-beat. [Formula: see text]O2musc was estimated by the approach as reported by Hoffmann et al. (Eur J Appl Physiol 113:1745-1754, 2013), accounting for circulatory distortions. Time constants (τ) for HR (τHR), [Formula: see text]O2pulm (τ [Formula: see text]O2pulm) and [Formula: see text]O2musc (τ [Formula: see text]O2musc) were estimated during the PRBS phases by time-series analysis.

Results: Peak oxygen uptake differed significantly between UpBody (37.8 ± 5.0 ml min(-1) kg(-1)) and LoBody exercises (56.1 ± 7.4 mL min(-1) kg(-1); p < 0.001). Significant differences were observed for τ [Formula: see text]O2musc (UpBody: 41.1 ± 11.3 s vs LoBody: 29.5 ± 5.2 s; p < 0.05), but not for τ [Formula: see text]O2pulm (49.1 ± 17.1 s vs 39.6 ± 11.2 s; p > 0.05) and τHR (29.1 ± 15.6 s vs 25.6 ± 8.0 s; p > 0.05).

Conclusions: Meaningful dissociations between [Formula: see text]O2pulm and [Formula: see text]O2musc kinetics exist for both UpBody and LoBody exercise during rapid work rate changes. Therefore, isolated [Formula: see text]O2pulm kinetic estimations without the consideration of the circulatory distortions may not allow a reliable assessment of [Formula: see text]O2musc kinetics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anaerobic Threshold / physiology
  • Arm / physiology
  • Exercise / physiology*
  • Exercise Test
  • Heart Rate / physiology*
  • Humans
  • Lung / metabolism
  • Male
  • Models, Statistical
  • Muscle, Skeletal / metabolism
  • Oxygen Consumption / physiology*
  • Stroke Volume / physiology
  • Young Adult