The effect of methylphenidate on sustained attention among adolescents with attention-deficit hyperactivity disorder

Neurocase. 2015;21(6):802-8. doi: 10.1080/13554794.2015.1023317. Epub 2015 Mar 16.

Abstract

Twenty-seven adolescents diagnosed as having attention-deficit hyperactivity disorder (ADHD) were tested twice with a computerized MATH-CPT (mathematics continuous performance test). In one administration, the participants took medication (methylphenidate, MPH) 1.5 hr before being tested. In another administration, the MATH-CPT was administered without the medication. Treatment with MPH improved the "overall attention level" and in measures of "reaction time" and "impulsivity." MPH did not improve the performance in the four measures of sustained attention. Knowing that treatment with MPH does not improve sustained attention can be helpful in reaching a decision of whether or not a child should be treated with MPH.

Keywords: computerized-testing; continuous-performance-test; mathematics continuous performance test; methylphenidate; sustained attention.

MeSH terms

  • Adolescent
  • Attention / drug effects*
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Central Nervous System Stimulants / administration & dosage
  • Central Nervous System Stimulants / therapeutic use*
  • Child
  • Female
  • Humans
  • Impulsive Behavior / drug effects
  • Male
  • Methylphenidate / administration & dosage
  • Methylphenidate / therapeutic use*
  • Reaction Time / drug effects
  • Treatment Outcome

Substances

  • Central Nervous System Stimulants
  • Methylphenidate