Background: Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue-derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC-CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of alopecia using ADSC-CM.
Objectives: This study evaluates our clinical experience in the use of ADSC-CM for the treatment of FPHL.
Methods: A retrospective, observational study of outcomes in 27 patients with FPHL treated with ADSC-CM was performed. To evaluate the efficacy of the treatment, patients' medical records and phototrichographic images were analyzed.
Results: The application of ADSC-CM showed efficacy in treating FPHL after 12 weeks of therapy. Hair density increased from 105.4 to 122.7 hairs/cm(2) (P < 0.001). Hair thickness increased from 57.5 μm to 64.0 μm (P < 0.001). None of the patients reported severe adverse reactions.
Conclusions: The application of ADSC-CM is a potential treatment option for FPHL.
© 2015 The International Society of Dermatology.