A photoinduced growth system of peptide nanofibres addressed by DNA hybridization

Masahiro Furutani; Akihito Uemura; Akira Shigenaga; Chiaki Komiya; Akira Otaka; Kazunori Matsuura

doi:10.1039/c5cc01452b

A photoinduced growth system of peptide nanofibres addressed by DNA hybridization

Chem Commun (Camb). 2015 May 11;51(38):8020-2. doi: 10.1039/c5cc01452b. Epub 2015 Mar 17.

Authors

Masahiro Furutani¹, Akihito Uemura, Akira Shigenaga, Chiaki Komiya, Akira Otaka, Kazunori Matsuura

Affiliation

¹ Graduate School of Engineering, Tottori University, 4-101 Koyama-Minami, Tottori 680-8552, Japan. ma2ra-k@chem.tottori-u.ac.jp.

PMID: 25778790
DOI: 10.1039/c5cc01452b

Abstract

Spatiotemporal control of peptide nanofibre growth was achieved by photocleavage of a DNA-conjugated β-sheet forming peptide that is linked through a photoresponsive amino acid residue. Peptide nanofibres were selectively formed by photocleaving the conjugate on a complementary DNA-immobilised glass substrate.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acids / chemistry
DNA, Complementary / chemistry*
Glass / chemistry
Nucleic Acid Hybridization*
Peptides / chemical synthesis
Peptides / chemistry*
Photochemical Processes
Ultraviolet Rays

Substances

Amino Acids
DNA, Complementary
Peptides