(111)In WBC SPECT/CT detection of a radiographically occult solitary infected renal cyst in polycystic kidney disease

Clin Nucl Med. 2015 Jun;40(6):542-4. doi: 10.1097/RLU.0000000000000771.


Renal cyst infection-pyocystis-is a potentially life-threatening complication of autosomal-dominant polycystic kidney disease. Differentiation of pyocystis from pyelonephritis is important for antibiotic management. A 56-year-old woman with autosomal-dominant polycystic kidney disease and recurrent urinary tract infections was admitted to the hospital with suspicion of pyelonephritis. CT and static planar In-labeled WBC examinations failed to show a specific focus of infection. Abdominal imaging with In-labeled WBC SPECT/CT revealed abnormal leukocyte accumulation within a solitary right renal cyst. Precise SPECT/CT localization of the infected renal cyst is illustrated along with comparative CT images.

Publication types

  • Case Reports

MeSH terms

  • Cysts / diagnostic imaging*
  • Cysts / pathology
  • Female
  • Humans
  • Indium Radioisotopes
  • Middle Aged
  • Multimodal Imaging
  • Polycystic Kidney, Autosomal Dominant / complications
  • Polycystic Kidney, Autosomal Dominant / diagnostic imaging*
  • Pyelonephritis / complications
  • Pyelonephritis / diagnostic imaging*
  • Radiopharmaceuticals
  • Tomography, Emission-Computed, Single-Photon*
  • Tomography, X-Ray Computed*
  • Urinary Tract Infections / complications
  • Urinary Tract Infections / diagnostic imaging*


  • Indium Radioisotopes
  • Radiopharmaceuticals