[The use of succinate-containing preparations in combine therapy of diffuse toxic goiter]

Klin Med (Mosk). 2014;92(8):50-3.
[Article in Russian]

Abstract

We studied dynamics of hormonal status, lipid peroxidation, protein oxidative modification, enzymatic activity of the antioxidative system in the patients with newly diagnosed diffuse toxic goiter (Graves' disease). It was shown that the use of succinate-containing antioxidant reamnberin accelerates normalization of hormonal status and free radical oxidation; it reduces the duration of hospitalization.

Publication types

  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Antithyroid Agents / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Graves Disease / blood
  • Graves Disease / drug therapy*
  • Humans
  • Male
  • Meglumine / administration & dosage
  • Meglumine / analogs & derivatives*
  • Meglumine / pharmacology
  • Middle Aged
  • Succinates / administration & dosage
  • Succinates / pharmacology*
  • Treatment Outcome

Substances

  • Antithyroid Agents
  • Reamberin
  • Succinates
  • Meglumine