Extensive superior limbic keratoconjunctivitis in Graves' disease: case report and mini-review of the literature

Clin Ophthalmol. 2015 Mar 10;9:467-8. doi: 10.2147/OPTH.S79561. eCollection 2015.


Background: Superior limbic keratoconjunctivitis (SLK) is characterized as an inflammation of the superior bulbar conjunctiva with predominant involvement of the superior limbus and adjacent epithelial keratitis.

Methods: A 51-year-old woman, with a history of medically controlled Graves' disease was seen with an extensive SLK involving 5 mm of the superior cornea.

Results: Total remission was observed with topical steroids (DXM). Recurrence was observed 1 week after steroid discontinuation, and steroidal treatment was reintroduced with tapering over 1 month. Total remission was then observed for 1 year.

Conclusion: Extensive keratitis and vascular pannus in SLK is rarely reported. This form could be treated with topical steroids. Tapering treatment remains essential for long-term success.

Keywords: Graves’ disease; anti-inflammatory drugs; dexamethasone; superior limbic keratoconjunctivitis; triamcinolone.

Publication types

  • Case Reports