All in the family: a portrait of a nuclear receptor co-activator complex

Charli B Fant; Dylan J Taatjes

doi:10.1016/j.molcel.2015.03.001

All in the family: a portrait of a nuclear receptor co-activator complex

Mol Cell. 2015 Mar 19;57(6):952-954. doi: 10.1016/j.molcel.2015.03.001.

Authors

Charli B Fant¹, Dylan J Taatjes²

Affiliations

¹ Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80303, USA.
² Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80303, USA. Electronic address: taatjes@colorado.edu.

Abstract

In this issue of Molecular Cell, Yi et al. (2015) use biochemical assays and cryo-EM to determine the molecular architecture of an estrogen receptor (ERα) co-activator complex bound to DNA.

Publication types

Comment

MeSH terms

E1A-Associated p300 Protein / chemistry*
Estrogen Receptor alpha / chemistry*
Humans
Nuclear Receptor Coactivator 3 / chemistry*

Substances

ESR1 protein, human
Estrogen Receptor alpha
E1A-Associated p300 Protein
EP300 protein, human
NCOA3 protein, human
Nuclear Receptor Coactivator 3

Abstract

Publication types

MeSH terms

Substances

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