Sinecatechins 10% ointment: a green tea extract for the treatment of external genital warts

Skin Therapy Lett. Jan-Feb 2015;20(1):6-8.

Abstract

External genital warts (EGWs) resulting from the human papilloma virus (HPV) are a common sexually transmitted infection and cause significant impairments in patient quality of life and sexual well-being. Therapeutic options for EGWs can be provider-assisted, but many patients opt for treatment that can be applied at home. Sinecatechins 10% ointment is a new botanically based patient-administered therapy for EGWs. It is comprised of >85% catechins, green tea polyphenols that have been shown to possess antioxidant, antiproliferative, antiviral, and antitumor properties. Phase III trials of sinecatechins 10% ointment have demonstrated higher efficacy and lower recurrence rates compared to currently available patient-applied treatments. Therefore, sinecatechins 10% ointment presents an alternative self-administered topical treatment for EGWs.

Publication types

  • Comparative Study

MeSH terms

  • Administration, Topical
  • Catechin / administration & dosage*
  • Catechin / pharmacology
  • Condylomata Acuminata / drug therapy*
  • Condylomata Acuminata / virology
  • Humans
  • Ointments
  • Papillomavirus Infections / drug therapy
  • Papillomavirus Infections / virology
  • Plant Extracts / administration & dosage*
  • Plant Extracts / pharmacology
  • Polyphenols / administration & dosage
  • Polyphenols / pharmacology
  • Quality of Life
  • Recurrence
  • Self Administration
  • Tea / chemistry

Substances

  • Ointments
  • Plant Extracts
  • Polyphenols
  • Tea
  • Catechin