Continuous measurement of intra-oral pH and temperature: development, validation of an appliance and a pilot study

J Oral Rehabil. 2015 Aug;42(8):563-70. doi: 10.1111/joor.12294. Epub 2015 Mar 21.

Abstract

To describe a novel approach for continuous measurement of intra-oral pH and temperature in individuals carrying out normal daily activities over 24 h. We designed, validated and constructed a custom-made appliance fitted with a pH probe and a thermocouple. Six subjects wore the appliance over a 24-h period for two non-consecutive days, while the intra-oral pH and temperature were measured continuously and recorded. Intra-oral pH and temperature were very similar across different recording days, the difference being not statistically significant (P ≥ 0.14). There was a noticeable difference in the pattern of variation of pH between day and night. During the day, the mean pH was 7.3 (±0.4) and dropped markedly only after consumption of acidic food and drinks. The intra-oral pH decreased slowly during sleep with an average pH of 6.6 (±0.4) being recorded. The difference between day and night was statistically significant (P = 0.002). The mean intra-oral temperature was 33.9 °C (±0.9) during daytime and 35·9 °C (±0·5) during sleep (P = 0.013) with minor fluctuations occurring over 24 h. The continuous and simultaneous intra-oral pH and temperature measurement system described in this report is reliable, easy to construct, able to measure variables over a sustained period and may serve as a future diagnostic tool in a number of applications.

Keywords: circadian rhythm; dental erosion; intra-oral pH; intra-oral temperature; salivary pH.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Body Temperature / physiology*
  • Circadian Clocks / physiology
  • Female
  • Humans
  • Hydrogen-Ion Concentration
  • Monitoring, Physiologic / instrumentation*
  • Mouth / physiology*
  • Pilot Projects