When the brain tells the blood how to clot

Blood. 2015 Mar 26;125(13):2015-6. doi: 10.1182/blood-2015-02-626515.


In this issue of Blood, Tian et al report that during traumatic brain injury, small membrane vesicles, called microparticles, disseminate procoagulant factors from the brain into the systemic circulation. The delivery appears to occur through the disrupted blood-brain barrier.

Publication types

  • Comment

MeSH terms

  • Animals
  • Blood Coagulation*
  • Brain / pathology*
  • Brain Injuries / blood*
  • Brain Injuries / pathology*
  • Cell-Derived Microparticles / physiology*
  • Humans
  • Male