Harnessing the heart of big data

Circ Res. 2015 Mar 27;116(7):1115-9. doi: 10.1161/CIRCRESAHA.115.306013.


The exponential increase in Big Data generation combined with limited capitalization on the wealth of information embedded within Big Data have prompted us to revisit our scientific discovery paradigms. A successful transition into this digital era of medicine holds great promise for advancing fundamental knowledge in biology, innovating human health and driving personalized medicine, however, this will require a drastic shift of research culture in how we conceptualize science and use data. An e-transformation will require global adoption and synergism among computational science, biomedical research and clinical domains.

Keywords: crowdsourcing; database; heart diseases; information storage and retrieval; metabolomics; proteomics; user-computer interface.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cardiology / statistics & numerical data*
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / therapy
  • Crowdsourcing
  • Data Display
  • Data Mining / trends*
  • Databases as Topic
  • Electronic Health Records
  • Forecasting
  • Humans
  • Information Science / organization & administration
  • Information Science / trends*
  • Information Systems / organization & administration
  • Knowledge Bases
  • Models, Theoretical
  • National Institutes of Health (U.S.)
  • Research / organization & administration
  • Software
  • United States
  • User-Computer Interface