Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid

Indian J Ophthalmol. 2015 Feb;63(2):117-21. doi: 10.4103/0301-4738.154377.


Background: Spectral domain enhanced depth imaging optical coherence tomography (EDI-OCT) can provide anatomic localization of intraocular tumors.

Aims: The aim was to identify topographical and intrinsic patterns of choroidal tumors on EDI-OCT.

Settings and design: Retrospective review.

Materials and methods: Analysis of published reports and personal observations using office based EDI-OCT.

Results: Using EDI-OCT, choroidal nevus displayed a smooth, dome-shaped topography with overlying retinal pigment epithelium alterations, drusen, and occasional subretinal cleft demonstrating photoreceptor loss. Small choroidal melanoma showed smooth, moderately dome-shaped topography, commonly with overlying shallow subretinal fluid that often depicted "shaggy" photoreceptors. Choroidal metastasis showed a minimally "lumpy, bumpy" surface topography and with overlying subretinal fluid and shaggy photoreceptors. Choroidal hemangioma showed a smooth, dome-shaped topography, with expansion of the affected small, medium, and large choroidal vessels. Choroidal lymphoma showed varying topography with increasing tumor thickness as "flat, rippled, or undulating (seasick)" surface. Choroidal osteoma displayed a smooth undulating surface with visible intralesional horizontal lines suggestive of bone lamellae and occasional horizontal and vertical tubules with intralesional "spongy" flecks. Choroidal melanocytosis appeared as uniformly thickened choroid with increased stromal density surrounding the normal choroidal vascular structures.

Conclusions: Enhanced depth imaging-OCT can depict characteristic patterns that are suggestive of various choroidal tumors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Choroid / pathology*
  • Choroid Neoplasms / diagnosis*
  • Diagnosis, Differential
  • Humans
  • Image Enhancement*
  • Tomography, Optical Coherence / methods*