How does fat survive and remodel after grafting?

Takanobu Mashiko; Kotaro Yoshimura

doi:10.1016/j.cps.2014.12.008

How does fat survive and remodel after grafting?

Clin Plast Surg. 2015 Apr;42(2):181-90. doi: 10.1016/j.cps.2014.12.008. Epub 2015 Jan 29.

Authors

Takanobu Mashiko¹, Kotaro Yoshimura²

Affiliations

¹ Department of Plastic Surgery, School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan.
² Department of Plastic Surgery, School of Medicine, University of Tokyo, 7-3-1, Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan. Electronic address: kotaro-yoshimura@umin.ac.jp.

PMID: 25827562
DOI: 10.1016/j.cps.2014.12.008

Abstract

Autologous fat grafting has become an important procedure for volumization and revitalization, although clinical outcomes depend greatly on technique. It was revealed recently how grafted fat tissue survives, regenerates, or dies. Experimental results provided the underlying mechanism and clinical implications for therapeutic strategies to maximize the effects of fat grafting, minimize necrosis, and avoid oil cyst formation.

Keywords: Adipose-derived stem/stromal cell; Fat grafting; Macrophages; Tissue regeneration; Vascular endothelial cells.

Publication types

Review

MeSH terms

Adipocytes / cytology*
Adipocytes / transplantation
Adipose Tissue* / blood supply
Adipose Tissue* / cytology
Adipose Tissue* / transplantation
Capillaries
Cell Count
Cell Survival
Humans
Tissue Survival