How does fat survive and remodel after grafting?

Clin Plast Surg. 2015 Apr;42(2):181-90. doi: 10.1016/j.cps.2014.12.008. Epub 2015 Jan 29.


Autologous fat grafting has become an important procedure for volumization and revitalization, although clinical outcomes depend greatly on technique. It was revealed recently how grafted fat tissue survives, regenerates, or dies. Experimental results provided the underlying mechanism and clinical implications for therapeutic strategies to maximize the effects of fat grafting, minimize necrosis, and avoid oil cyst formation.

Keywords: Adipose-derived stem/stromal cell; Fat grafting; Macrophages; Tissue regeneration; Vascular endothelial cells.

Publication types

  • Review

MeSH terms

  • Adipocytes / cytology*
  • Adipocytes / transplantation
  • Adipose Tissue* / blood supply
  • Adipose Tissue* / cytology
  • Adipose Tissue* / transplantation
  • Capillaries
  • Cell Count
  • Cell Survival
  • Humans
  • Tissue Survival