Rhabdomyolysis: pathogenesis, diagnosis, and treatment

Ochsner J. Spring 2015;15(1):58-69.


Background: Rhabdomyolysis is a complex medical condition involving the rapid dissolution of damaged or injured skeletal muscle.

Methods: This review focuses on the epidemiology, pathophysiology, causes, presentation, diagnosis, complications, management, and anesthetic considerations related to rhabdomyolysis.

Results: Any form of muscle damage--and by extension any entity that causes muscle damage--can initiate rhabdomyolysis. One of the most important treatment goals when rhabdomyolysis is suspected is avoiding acute kidney injury.

Conclusion: All clinicians should be aware of common causes, diagnosis, and treatment options.

Keywords: Rhabdomyolysis.

Publication types

  • Review