Successful treatment of an invasive fungal infection caused by Talaromyces sp. with voriconazole

Uluhan Sili; Huseyin Bilgin; Rikesh Masania; Emel Eryuksel; Nuri Cagatay Cimsit; Gulcicek Ayranci; Malcolm Richardson; Volkan Korten

doi:10.1016/j.mmcr.2015.02.002

Successful treatment of an invasive fungal infection caused by Talaromyces sp. with voriconazole

Med Mycol Case Rep. 2015 Feb 24:8:21-3. doi: 10.1016/j.mmcr.2015.02.002. eCollection 2015 Jun.

Authors

Uluhan Sili¹, Huseyin Bilgin¹, Rikesh Masania², Emel Eryuksel³, Nuri Cagatay Cimsit⁴, Gulcicek Ayranci⁵, Malcolm Richardson², Volkan Korten¹

Affiliations

¹ Department of Infectious Diseases and Clinical Microbiology, School of Medicine, Marmara University, Istanbul, Turkey.
² Mycology Reference Centre, University Hospital of South Manchester, Manchester, and Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester, UK.
³ Department of Pulmonary and Critical Care, School of Medicine, Marmara University, Istanbul, Turkey.
⁴ Department of Radiology, School of Medicine, Marmara University, Istanbul, Turkey.
⁵ Department of Pathology, School of Medicine, Marmara University, Istanbul, Turkey.

Abstract

Invasive fungal infections (IFI) are on the rise due to increasing numbers of immunosuppressed and critically ill patients. A malignant-looking pulmonary nodule in an immunosuppressed patient may indeed be caused by a fungal organism. We report a patient, who was eventually diagnosed with an IFI caused by an agent of hyalohyphomycosis, Talaromyces sp. determined via molecular methods and succesfully treated with voriconazole.

Keywords: Invasive fungal infection; Mold infection; Rheumatoid arthritis; Voriconazole.