Convergence of anatomy, technology, and therapeutics: a review of laser-assisted drug delivers

Semin Cutan Med Surg. 2014 Dec;33(4):176-81. doi: 10.12788/j.sder.0119.


This is a very exciting time in cutaneous laser surgery with an ever-expanding therapeutic armamentarium and an increased sophistication of available technology. These recent trends have allowed for both a rapid development of interest and exploration of laser-assisted drug delivery and its potential applications. We review the current literature on anatomy, technology, and therapeutics as it relates to laser-assisted drug delivery. The focus of our review is on two areas of interest that have received much attention to date - photodynamic therapy in the treatment of actinic keratoses and nonmelanoma skin cancers as well as the treatment of scarring. We will also discuss potential complications of existing modalities used independently and in laser-assisted drug delivery and conclude with future indications for this burgeoning therapeutic methodology.

Publication types

  • Review

MeSH terms

  • Cicatrix / therapy
  • Drug Delivery Systems / instrumentation*
  • Humans
  • Keratosis, Actinic / therapy
  • Laser Therapy*
  • Lasers*
  • Photochemotherapy*
  • Skin / anatomy & histology
  • Skin Neoplasms / therapy