Exercise-induced lipid peroxidation and leakage of enzymes before and after vitamin E supplementation

Int J Biochem. 1989;21(8):835-8. doi: 10.1016/0020-711x(89)90280-2.


1. The purpose of this study was to investigate the effects of vitamin E on serum levels of malondialdehyde following the acute exhaustive exercise in human, and to determine whether the magnitude of leakage of enzyme would be affected by vitamin E supplementation. 2. Increase of malondialdehyde after exercise before vitamin E supplementation was slight (but statistically significant), however after supplementation with vitamin E, malondialdehyde level after exercise was significantly decreased. 3. Leakage of enzyme was significantly increased after exercise before vitamin E supplementation, but it was lower following exercise after vitamin E supplementation. 4. Lipid peroxidation following a bout of acute heavy exercise can be inhibited by vitamin E supplementation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aspartate Aminotransferases / blood*
  • Glucuronidase / blood*
  • Hematocrit
  • Humans
  • Lipid Peroxidation / drug effects
  • Lipid Peroxidation / physiology*
  • Male
  • Malondialdehyde / blood
  • Physical Exertion / physiology*
  • Uric Acid / blood
  • Vitamin E / pharmacology*


  • Vitamin E
  • Uric Acid
  • Malondialdehyde
  • Aspartate Aminotransferases
  • Glucuronidase