Fournier's ganrene in the HIV era

Afr Health Sci. 2014 Dec;14(4):1063-8. doi: 10.4314/ahs.v14i4.38.

Abstract

Background: Fournier's gangrene is a devastating condition that affects mostly patients whose immunity has been reduced. There is increasing evidence for increasing incidence of the disease in those with HIV disease.

Objective: To evaluate the presentation, bacteriology and outcome of Fournier's gangrene in our area in recent times in view of the high prevalence in Nairobi and its environs.

Results: One hundred and forty six patients were treated for Fournier's gangrene during the study period; all were male. They had a mean age of 38.6 years (range 2 months - 86 years). HIV infection was the most common associated underlying illness (16.4 %), followed by diabetes mellitus and alcoholism (11%).

Conclusions: HIV infection is emerging as leading predisposing factor and has overtaken diabetes in predisposing for Fournier's gangrene in Kenyatta National Hospital.

Keywords: Fournier's gangrene; HIV.

Publication types

  • Evaluation Study

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology*
  • AIDS-Related Opportunistic Infections / pathology
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Child, Preschool
  • Debridement
  • Fournier Gangrene / epidemiology*
  • Fournier Gangrene / therapy
  • HIV Infections / complications*
  • Humans
  • Infant
  • Kenya / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult

Substances

  • Anti-Bacterial Agents