Seeing double: sertraline and diplopia: a case report

Int J Psychiatry Med. 2015;49(1):107-10. doi: 10.2190/PM.49.1.h.


Objective: To describe the first case of sertraline-induced diplopia.

Method: Medline and PubMed data search using the words sertraline, Zoloft, diplopia, double vision. A case summary of a patient who developed diplopia from sertraline.

Result: This case describes a 34-year-old man who developed diplopia after treatment with sertraline. The diplopia resolved after discontinuation of sertraline and redeveloped upon rechallenge.

Conclusion: Although incidences of diplopia caused by citalopram, another SSRI, have been described, to the best of our knowledge, this is the first reported case of sertraline-induced diplopia. More studies are needed to describe the full mechanism of action of sertraline-induced diplopia.

Keywords: SSRI; Zoloft; diplopia; sertraline.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Depressive Disorder, Major / diagnosis
  • Depressive Disorder, Major / drug therapy*
  • Depressive Disorder, Major / psychology
  • Diplopia / chemically induced*
  • Diplopia / diagnosis
  • Humans
  • Male
  • Photophobia / chemically induced
  • Photophobia / diagnosis
  • Photophobia / psychology
  • Sertraline / adverse effects*
  • Sertraline / therapeutic use
  • Stress Disorders, Post-Traumatic / diagnosis
  • Stress Disorders, Post-Traumatic / drug therapy*
  • Stress Disorders, Post-Traumatic / psychology
  • Visual Acuity / drug effects


  • Sertraline