Reshaping procedures for the surgical management of corneal ectasia

J Cataract Refract Surg. 2015 Apr;41(4):842-72. doi: 10.1016/j.jcrs.2015.03.010.


Corneal ectasia is a progressive, degenerative, and noninflammatory thinning disorder of the cornea. Recently developed corneal reshaping techniques have expanded the treatment armamentarium available to the corneal specialist by offering effective nontransplant options. This review summarizes the current evidence base for corneal collagen crosslinking, topography-guided photorefractive keratectomy, and intrastromal corneal ring segment implantation for the treatment of corneal ectasia by analyzing the data published between the years 2000 and 2014.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

Publication types

  • Review

MeSH terms

  • Collagen / metabolism
  • Corneal Stroma / drug effects*
  • Corneal Stroma / metabolism
  • Cross-Linking Reagents
  • Dilatation, Pathologic / surgery
  • Humans
  • Keratoconus / surgery*
  • Photorefractive Keratectomy*
  • Photosensitizing Agents / therapeutic use*
  • Prostheses and Implants
  • Prosthesis Implantation*


  • Cross-Linking Reagents
  • Photosensitizing Agents
  • Collagen