Relationship between Cardio-Ankle Vascular Index (CAVI) and Obstructive Sleep Apnea (OSA)

J Med Assoc Thai. 2015 Feb;98(2):156-62.

Abstract

Background and objective: A non-invasive test called Cardio-Ankle Vascular Index (CA VI) measures aortic stiffness, which is an early sign of atherosclerosis. Obstructive sleep apnea (OSA) has a close association with cardiovascular mortality and morbidity. We sought to assess the relationship between OSA and arterial stiffness.

Material and method: Seventy-one patients with OSA (apnea-hypopnea index AHI ≥ 5, mean age 51.5 ± 14.1 years, 27 females) and 11 controls (AHI < 5, mean age 56.8 ± 11.8 years, 5 females) were enrolled in the study. In all subjects, arterial stiffness (CAVI) was performed and recorded along with blood pressure, pulse pressure of brachial arteries, and ankle arteries.

Results: The demographic data of the patients with OSA and controls were not significantly different. Subjects with OSA demonstrated higher values ofmean ankle artery pulse pressure than the controls (73.1 ± 14.6 vs. 59.6 ± 6.1 mmHg, respectively), but arterial stiffness and CAVI had no statistically significant difference (7.47 ± 1.68 vs. 7.25 ± 1.61, respectively).

Conclusion: There was no relationship between arterial stiffness CAVI, and the presence of OSA. However; there was a significant association between ankle artery pulse pressure and the presence of OSA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Ankle / blood supply*
  • Ankle Brachial Index
  • Blood Pressure
  • Brachial Artery / physiopathology*
  • Case-Control Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Sleep Apnea, Obstructive / physiopathology*
  • Vascular Stiffness / physiology*