Rejuvenating immunity: "anti-aging drug today" eight years later

Oncotarget. 2015 Aug 14;6(23):19405-12. doi: 10.18632/oncotarget.3740.

Abstract

The 2014 year ended with celebration: Everolimus, a rapamycin analog, was shown to improve immunity in old humans, heralding "a turning point" in research and new era in human quest for immortality. Yet, this turning point was predicted a decade ago. But what will cause human death, when aging will be abolished?

Keywords: TOR; diseases; gerosuppression; lifespan; longevity; mTOR; rapalogs.

MeSH terms

  • Aging / drug effects*
  • Aging / immunology
  • Animals
  • Everolimus / administration & dosage*
  • Everolimus / pharmacology*
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Immunosuppressive Agents / pharmacology*
  • Longevity / drug effects*
  • Longevity / immunology

Substances

  • Immunosuppressive Agents
  • Everolimus