Hyphenated low-field NMR techniques: combining NMR with NIR, GPC/SEC and rheometry

Magn Reson Chem. 2016 Jun;54(6):494-501. doi: 10.1002/mrc.4219. Epub 2015 Apr 9.

Abstract

Hyphenated low-field NMR techniques are promising characterization methods for online process analytics and comprehensive offline studies of soft materials. By combining different analytical methods with low-field NMR, information on chemical and physical properties can be correlated with molecular dynamics and complementary chemical information. In this review, we present three hyphenated low-field NMR techniques: a combination of near-infrared spectroscopy and time-domain NMR (TD-NMR) relaxometry, online (1) H-NMR spectroscopy measured directly after size exclusion chromatographic (SEC, also known as GPC) separation and a combination of rheometry and TD-NMR relaxometry for highly viscous materials. Case studies are reviewed that underline the possibilities and challenges of the different hyphenated low-field NMR methods. Copyright © 2015 John Wiley & Sons, Ltd.

Keywords: NIR-NMR; SEC-NMR; TD-NMR; hyphenated methods; low-field NMR; relaxometry; rheoNMR.