Cell-based screening: extracting meaning from complex data

Neuron. 2015 Apr 8;86(1):160-74. doi: 10.1016/j.neuron.2015.02.023.


Unbiased discovery approaches have the potential to uncover neurobiological insights into CNS disease and lead to the development of therapies. Here, we review lessons learned from imaging-based screening approaches and recent advances in these areas, including powerful new computational tools to synthesize complex data into more useful knowledge that can reliably guide future research and development.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Central Nervous System Diseases / therapy
  • Computer Simulation
  • Databases, Factual*
  • Humans
  • Induced Pluripotent Stem Cells / physiology*
  • Research*