Gut microbiota: the link to your second brain

Cell. 2015 Apr 9;161(2):193-4. doi: 10.1016/j.cell.2015.03.033.


Serotonin is a highly ubiquitous signaling molecule that plays a role in the regulation of various physiological functions. Several lines of evidence, including the present work from Hsiao and colleagues, demonstrate that, in the gut, microbial-derived metabolites affect the production of serotonin that in turn impacts host physiological functions.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bacteria / metabolism*
  • Gastrointestinal Tract / microbiology*
  • Humans
  • Microbiota*
  • Serotonin / biosynthesis*


  • Serotonin