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Practice Guideline
. 2015 May;110(5):646-59; quiz 660.
doi: 10.1038/ajg.2015.112. Epub 2015 Apr 14.

ACG Clinical Guideline: Primary Sclerosing Cholangitis

Keith D Lindor  1 , Kris V Kowdley  2 , M Edwyn Harrison  3 ; American College of Gastroenterology
Affiliations
Practice Guideline

ACG Clinical Guideline: Primary Sclerosing Cholangitis

Keith D Lindor et al. Am J Gastroenterol. 2015 May.

Abstract

Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursodeoxycholic acid is used by many on an empiric basis. Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.

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